Regulation of colominic acid biosynthesis by temperature: Role of cytidine 5′-monophosphateN-acetylneuraminic acid synthetase
نویسندگان
چکیده
منابع مشابه
Colominic Acid, a Polymer of N-acetylneuraminic Acid
All acidic carbohydrate has been isolated from the culture medium of the enteric microorganism E. coli K(235) L(+)O. This substance has been named colominic acid. N-acetylneuraminic acid, which has been isolated from the hydrolysate of colominic acid, is believed to be the monomer unit from which colominic acid is constituted. Colominic acid is not antigenic in rabbits. Tests have failed to rev...
متن کاملEnzymatic synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid.
We have established an efficient method for enzymatic production of cytidine 5'-monophospho-N-acetylneuraminic acid (CMP-NeuAc) from inexpensive materials, N-acetylglucosamine (GlcNAc) and cytidine 5'-monophosphate (CMP). The Haemophilus influenzae nanE gene encoding GlcNAc 6-phosphate (GlcNAc 6-P) 2-epimerase and the Campylobacter jejuni neuB1 gene encoding N-acetylneuraminic acid (NeuAc) synt...
متن کاملMammalian cytidine 5'-monophosphate N-acetylneuraminic acid synthetase: a nuclear protein with evolutionarily conserved structural motifs.
Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is species- and tissue-specific, is highly regulated during embryonic development, and changes with stages of differentiation. A prerequisite for the synthesis of sialylated glycoconjugates is the activated sugar-nucleotide cytid...
متن کاملCytidine Monophospho-N- Acetylneuraminic Acid Hydroxylase (CMAH)
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1560 Databanks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1561 Name and History . . . ....
متن کاملThe Biosynthesis of Cytidine 5’-Monophospho-IV-acetylneuraminic Acid by an Enzyme from Neisseriu meni@i&s*
In the accompanying paper (2) it was shown that Neisseria meningitidis, strain 1908 (Group C), forms N-acetylneuraminic acid by the condensation of N-acetyl-n-mannosamine and phosphoenolpyruvate with elimination of the phosphate group. In a preliminary communication we have reported a neK type of reaction carried out by another enzyme of Ncisserio meningitidis, strain 1998, which might be consi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Letters
سال: 1989
ISSN: 0014-5793
DOI: 10.1016/0014-5793(89)80770-7